ClpP inhibitor M21 ( —— )

产品货号. M10535 CAS No. 1151944-58-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

ClpP inhibitor M21
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

ClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM.
产品描述

ClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM, inhibits ClpP cleavage of SUc-LY-AMC substrate in a peptidase assay; alters α-toxin expression in a ClpP-dependent manner and attenuate S. aureus virulence via ClpP inhibition; blocks the pathogenicity of infection in animal models.
同义词

——
通路

GPCR/G Protein
靶点

Antibacterial
受体

Antibacterial
研究领域

——
适应症

——

CAS Number

1151944-58-9
分子量

385.45
分子式

C19H15NO4S2
纯度

>98% (HPLC)
溶解度

——
SMILES

C1=CC=C(C=C1)COC2=CC=C(C=C2)C=C3C(=O)N(C(=S)S3)CC(=O)O
化学全称

(Z)-2-(5-(4-(benzyloxy)benzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid

1. Gao P, et al. Proc Natl Acad Sci U S A. 2018 Jul 16. pii: 201720520.

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产品手册

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